Ultra-low Temperature Technology
Ultra-low temperature reactions are typically highly selective and hence are effective in improving process yield and product purity. The most typical ultra-low temperature reaction is metallation, which is widely used in syntheses of high-valued aromatic boric acid, aldehyde, acid and ester etc.

Heterocyclic reaction
Habotech specializes in heterocyclic reactions (especially N-heterocyclic reactions) and has rich experience in heterocyclic reactions. Habotech specializes in synthesizing and processing various heterocyclic reactions

Grignard reaction
Halogenated hydrocarbon in THF react with magnesium to prepare magnesium alkyl RMgX, grignard reagent can take addition reaction with the aldehyde, ketone compounds , produce alcohol after hydrolysis, grignard reagent is not only a strong alkali, but also a very strong nucleophilic reagent, very active, easily react with water, carbon dioxide and alcohols, aldehydes, ketones, esters, aminesand epoxides , produce various types of organic compounds.

1. Nucleophilic fluorination, 2. Electrophilic fluorination, 3.Application of fluorinated block,5.halogen-exchange,6 derivative reaction of fluoride

Suzuki coupling reaction
Especially used in the field of drug synthesis, it plays a very important role in the synthesis of API N+1, N+2 and N+3.Under palladium catalysis,organic boron compounds were coupled with organic halogen compounds.This type of coupling reaction has some prominent advantages.Such as,1.The reaction is not sensitive to water 2. Multiple active functional groups are allowed to exist; 3. The ability to carry out the usual regional and stereo selective reactions, especially , the inorganic by-products of such reactions are non-toxic and easy to remove, making them suitable not only for lab use but also for industrial production.